Preparation and Characterization of Resveratrol Microemulsions
- VernacularTitle:白藜芦醇微乳的制备及表征
- Author:
Guang YANG
;
Xiangyang XIE
;
Yanling SONG
- Publication Type:Journal Article
- Keywords:
Resveratrol;
Microemulsions;
High pressure homogenization method
- From:
China Pharmacist
2015;(3):414-419
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To prepare resveratrol microemulsions by high pressure homogenization method and characterize the microe-mulsions. Methods:Using the particle size, polydispersion index and encapsulation efficiency as the indicators, the independent varia-bles of the preparation were inspected, and the microemulsions were characterized. The stability of resveratrol microemulsions was stud-ied by long term stability test preliminarily. Results:The mean particle size, polydispersion index and zeta potential of resveratrol mi-croemulsions was (231 ± 37. 8) nm, 0. 228 ± 0. 047 and ( -42. 5 ± 4. 3) mV, respectively. The microemulsions were found to be small and spherical with smooth surface under a transmission electron microscope. Long term stability studies showed that the microe-mulsions were stable in 3 months after stored at 25℃. Conclusion:The preparation process of high pressure homogenization method for resveratrol microemulsions is simple and feasible.
