Advances in Pharmacological Actions and Mechanisms of Doxycycline in the Inhibition of Matrix Metallo-proteinase
- VernacularTitle:多西环素抑制金属蛋白酶药理作用及机制研究进展
- Author:
Wei CHEN
;
Xiang FU
;
Liyingzi HUANG
;
Liujun MAO
;
Lilin DAI
- Publication Type:Journal Article
- Keywords:
Doxycycline;
Pharmacological actions;
Matrix metalloproteinase
- From:
China Pharmacist
2015;(3):482-484
- CountryChina
- Language:Chinese
-
Abstract:
Doxycycline is a broad-spectrum antimicrobial agent used in clinical for a long time. In recent years, many studies showed that its pharmacological activities of anti-tumor, heart function improvement, nerve protection and antiasthma depended on its inhibition of matrix metalloproteinase ( MMPs) . In the present paper,the new pharmacological actions of doxycycline were reviewed to promote the applications in clinics.
