Imaging findings of spinal giant cell tumor

Yu Gao; Xiaohui MA; Wei Zhang; Jian Zhao; Shiling LI; Zhenjiang Zhao; Jie Liu; Yan Song; Zhen Jiang

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Imaging findings of spinal giant cell tumor

VernacularTitle:脊柱骨巨细胞瘤影像学表现
Author: Yu GAO ; Xiaohui MA ; Wei ZHANG ; Jian ZHAO ; Shiling LI ; Zhenjiang ZHAO ; Jie LIU ; Yan SONG ; Zhen JIANG
Publication Type:Journal Article
Keywords: spine; giant cell tumors; imaging feature
From: Journal of Practical Radiology 2014;(7):1165-1168
CountryChina
Language:Chinese
Abstract: Objective To improve the accuracy of diagnosis and differential diagnosis by summarizing imaging characteristics of spinal giant cell tumor of bone (GCTB).Methods Total 28 cases of spinal GCT were confirmed by pathology,of which 2 localized in cervical vertebra,8 in thoracic vertebra,8 in lumbar vertebra,and the other 10 lesions in the sacrum.All patients underwent X-ray,CT,and MRI scanning.Results (1)The incidence of spinal GCTB in the sacrum is highest,up to 35.7%.Lesions can locate in single or more vertebral bodies.All of the 10 cases with primary lesion locating the sacrum were involved in more vertebral bodies. (2)X-ray and CT showed central or eccentric vertebral destruction with 22 cases involving in adnexal bones,21 cases with bone crest or bony septum and 26 cases with soft tissue mass.(3)Lesions examined with MRI showed inhomogeneous isointense or slight hy-pointense on T1 WI,inhomogeneous hyperintense or isointense on T2 WI and inhomogeneous hyperintense or slight hyperintense on STIR.(4)Expansive bone destruction and soft tissue mass occurred again in postoperative recurrent lesions.Conclusion X-ray,CT and MRI are of significant value in the diagnosis of the spinal GCT.The combination of the three is helpful to improve the accuracy of diagnosis and differential diagnosis.