Research progress of stem cell-derived RPE cell transplantation therapy for retinal degenerative diseases
10.3980/j.issn.1672-5123.2017.12.17
- VernacularTitle:干细胞来源的RPE细胞移植治疗视网膜退行性疾病的研究进展
- Author:
Cao TIAN-YUE
1
;
Jiang SHUANG-HONG
;
Yan CHEN
;
Ai MING
Author Information
1. 430060 中国湖北省武汉市,武汉大学人民医院眼科
- Keywords:
degenerative retinal dieases;
age-related macular degeneration;
stem cell-based therapy;
retinal pigment epithelium
- From:
International Eye Science
2017;17(12):2260-2262
- CountryChina
- Language:Chinese
-
Abstract:
·Age - related macular degeneration ( ARMD ) and Stargardt's macular dystrophy ( SMD ) are two kinds of degenerative retinal diseases that respectively lead to irreversible vision loss of the elderly and juvenile population. However, the severe visual impairment in dry ARMD and SMD remains untreatable. In recent years, with the advancement of stem cell technology, stem cell-derived RPE cell transplantation therapy of retinal degeneration has become new research hotspot and direction. This article reviewed the progress of stem cell based approaches for treating retinal degenerative diseases and discussed the prospect and challenges in this field.
