Analysis of influence factors for spontaneous closure of atrial septal defect and ventricular septal defect in the northern of Xinjiang
10.7683/xxyxyxb.2017.11.014
- VernacularTitle:新疆北疆地区房间隔缺损和室间隔缺损自然闭合影响因素分析
- Author:
bin Yan WANG
1
;
yan Chun GUO
;
lin Yong CHEN
;
yong Jin PAN
;
rong Hui ZHANG
Author Information
1. 河南科技大学第一附属医院儿科
- Keywords:
the northern of Xinjiang;
atrial septal defect;
ventricular septal defect;
spontaneous closure
- From:
Journal of Xinxiang Medical College
2017;34(11):1008-1011
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyse the risk factors for spontaneous closure of atrial septal defect(ASD) and ventricular septal defect(VSD) in children in the northern of Xinjiang.Methods Ninety-two ASD and sixty-five VSD children in Department of Pediatrics,the First Affiliated Hospital of Medical College,Shehezi University from January 2010 to May 2014 were selected as research subject.According to the spontaneous closure condition of children,the children with ASD were divided into ASD spontaneous closure group and ASD non spontaneous closure group;the children with VSD were divided into VSD spontaneous closure group and VSD non spontaneous closure group.The risk factors for spontaneous closure of ASD and VSD were analysed by single factor and multiple factor logistic regression analysis.Results In 92 ASD children,12 cases (13.04％) were spontaneous closure.In 65 VSD children,9 cases (13.85％) were spontaneous closure.Single factor analysis result showed that there was statistic difference in defect diameter,defect type and the age between spontaneous closure group and non spontaneous closure group in ASD and VSD children (P ＜ 0.05);but there was no statistic difference in defect number and complications between spontaneous closure group and non spontaneous closure group in ASD and VSD children (P ＞ 0.05).Multivariate logistic regression analysis showed that the defect diameter,defect type and the age were the independent risk factors for the spontaneous closure of ASD and VSD (P ＜ 0.05).Conclusion The age ＜ 2 years old,central ASD,perimembranous VSD and defect diameter ＜ 5 mm are important factors for promoting spontaneous closure of ASD and VSD.
