Application value of procalcitonin, cholinesterase and cardiac troponin Ⅰ in the evaluation of disease degree and prognosis of sepsis patients
10.7683/xxyxyxb.2017.12.017
- VernacularTitle:降钙素原、胆碱酯酶及心肌肌钙蛋白Ⅰ在脓毒症患者病情及预后评估中的应用价值
- Author:
ping Ya LI
1
;
lin Jun ZHANG
Author Information
1. 黄冈市中心医院感染科
- Keywords:
sepsis;
procalcitonin;
cholinesterase;
cardiac troponin Ⅰ;
prognosis
- From:Journal of Xinxiang Medical College
2017;34(12):1111-1113
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the application value of procalcitonin (PCT),cholinesterase (CHE) and cardiac troponin Ⅰ (cTnⅠ) in the evaluation of disease degree and prognosis of sepsis patients,so as to provide the basis for clinical diagnosis and prognostic evaluation of sepsis.Methods A total of 114 patients with sepsis were selected in Huanggang Central Hospital from May 2014 to June 2016.The patients were divided into sepsis group (n =47),severe sepsis group (n =42) and septic shock group (n =25) according to the severity of the disease.The patients were divided into death group (n =23) and survival group (n =91) according to the survival status.The levels of serum PCT,CHE and cTnⅠ were compared in the groups.Results The levels of serum PCT and cTnI in septic shock group were significantly higher than those in severe sepsis group and sepsis group (P < 0.05).The levels of serum PCT and cTnⅠ in severe sepsis group were significantly higher than those in sepsis group (P < 0.05).The level of serum CHE in septic shock group was significantly lower than that in severe sepsis group and sepsis group (P < 0.05),and the serum CHE level in severe sepsis group was significantly lower than that in sepsis group (P < 0.05).The levels of serum PCT and cTnI in the death group were significantly higher than those in the survival group (P < 0.05),and the serum CHE level in the death group was significantly lower than that in the survival group (P < 0.05).Conclusion The levels of serum PCT,CHE and cTnⅠ are important in evaluating the severity and prognosis of patients with sepsis.