A study of risk factors and predictive factors in intraoperative floppy iris syndrome during phacoemulsification

VernacularTitle:白内障超声乳化术中虹膜松弛综合征发生的新危险因素和预测指标
Author: Yu JIE-XIN ¹ ; Yao KE
Author Information

1. 浙江中医药大学附属第一医院眼科
Keywords: intraoperative floppy iris syndrome; risk factors; predictive factors; complication
From: International Eye Science 2017;17(11):2126-2129
CountryChina
Language:Chinese
Abstract: AIM:To determine the incidence of intraoperative floppy iris syndrome (IFIS) in patients undergoing phacoemulsification in a Chinese hospital,and to assess new risk factors and predictive factors for IFIS.METHODS:A prospective,observational case series.In the consecutive cataract surgeries performed in one year,the medicine administration,pupil size (PS)before and after mydriasis,and signs of IFIS were recorded.RESULTS:Totally 807 patients (1068 eyes) underwent cataract surgeries.Among the 1068 eyes,signs of IFIS were noted in 34 eyes.Strong positive correlations were showed between finasteride (6.4％,OR =5.885),tamsulosin (25％,OR=21.578),reserpine (16.7％,OR=12.947),clozapine (66.7％,OR=139.467),post-panretinal photocoagulation (14.3％,OR =10.789) and IFIS.Pupil size was inversely related to IFIS incidence (P＜0.001).A dilated pupil smaller than 7.25mm could predict iFiS (P＜0.001).CONCLUSION:The incidence rate of IFIS was 3.18％.Reserpine,clozapine and post-panretinal photocoagulation emerged as new risk factors for IFIS.A small dilated pupil may imply IFIS occurrence.