Clinical effect of tocilizumab on patients with severe active rheumatoid arthritis
10.11817/j.issn.1672-7347.2017.10.008
- VernacularTitle:托珠单抗治疗重症活动性类风湿关节炎的疗效
- Author:
Suqing XU
1
;
Xi XIE
;
Mengshi TANG
;
Jinwei CHEN
;
Jing TIAN
;
Jinfeng DU
;
Ni MAO
;
Yiming LIU
;
Shu LI
Author Information
1. 中南大学湘雅二医院风湿免疫科
- Keywords:
interleukin-6;
biological agent;
tocilizumab;
rheumatoid arthritis
- From:
Journal of Central South University(Medical Sciences)
2017;42(10):1174-1177
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate therapeutic effects and adverse reactions of tocilizumab on patients with severe active rheumatoid arthritis (RA).Methods:Twelve patients with severe refractory RA were treated with tocilizumab.The clinical and laboratory indices and the side effects were recorded after treatment.Results:The clinical and laboratory indices and the disease activity score 28 (DAS28) were observed in all patients,which were significantly improved after TCZ therapy (P＜0.05),and no obvious adverse reactions were found.Conclusion:Tocilizumab can effectively relieve the symptoms and improve the conditions of severe active RA.
