Changes in retinal microstructure in patients with rhegmatogenous retinal detachment and its association with BCVA
10.13389/j.cnki.rao.2017.0286
- VernacularTitle:孔源性视网膜脱离患者术后视网膜微结构改变及其与视功能的相关关系
- Author:
Gai Hong YAN
1
;
Jun LI
;
Ping Hong NIE
;
Jie Shi ZHANG
;
Liu YANG
Author Information
1. 北京大学第一医院视觉损伤与修复教育部重点实验室
- Keywords:
rhegmatogenous retina[detachment;
retinal microstructure;
best corrected visual acuity
- From:
Recent Advances in Ophthalmology
2017;37(12):1135-1138,1142
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the retinal microstructure changes in patients with rhegmatogenous retinal detachment following vitrectomy procedures and its correlation with the best corrected visual acuity (BCVA).Methods Patients who were diagnosed with rhegmatogenous retinal detachment and underwent vitrectomy were recruited in this study.BCVA and optical coherence tomography (OCT) examination were performed at 1 week,1 month,3 months and 6 months after operation for recording the neurosensory retinal thickness and outer nuclear layer thickness as well as observing the occurrence of ellipsoid zone,external limiting membrane rupture,macuiar edema,macular epiretinal membrane.Results A total of 32 eyes from 31 patients were followed up,and the BCVA became better as the follow-up prolonged.Both neurosensory retinal thickness and outer nuclear layer thickness thickened from 1 week [(122.75 ± 111.84) μm and (79.06 ±76.67) μm] to 3 months [(163.28 ± 133.10) μm and (108.66 ± 120.40)μm],and slightly thinned at 6 months [(159.50 ± 99.26) μm and (99.22 ± 74.89) μm].AS follow-up went by,the occurrence rate of ellipsoid zone and external limiting membrane rupture were 68.8% and 53.1%,65.6% and 46.9%,56.3% and 40.6%,50.0% and 37.5% at 1 week,1 month,3 months,6 months,respectively,and both variables were significantly correlation with the patients' BCVA.Conclusion The neurosensory retinal thickness and outer nuclear layer thickness in patients with rhegmatogenous retinal detachment became gradually thicker and the vision became better during follow-up.Meanwhile,the ellipsoid zone and external limiting membrane rupture are the key factors for patients' BCVA.