Systemic inflammatory response syndrome after percutaneous nephrolithotomy: an assessment of risk factors
10.3760/cma.j.issn.1000-6702.2017.11.013
- VernacularTitle:经皮肾镜取石术后全身炎症反应综合征的相关危险因素分析
- Author:
Junhong FAN
1
;
Wenqi WU
;
Wei ZHU
;
Chuangxin LAN
;
Dong CHEN
;
Xiaolu DUAN
;
Yang LIU
;
Yu LAN
;
Tao ZENG
;
Guohua ZENG
Author Information
1. 510230,广州医科大学附属第一医院微创外科中心泌尿外科 广东省泌尿外科重点实验室
- Keywords:
Percutaneous nephrolithotomy;
Kidney stone;
Systemic inflammatory response syndrome;
Risk factors
- From:
Chinese Journal of Urology
2017;38(11):857-861
- CountryChina
- Language:Chinese
-
Abstract:
Objective To identify risk factors of systemic inflammatory response syndrome (SIRS) after percutaneous nephrolithotomy (PCNL).Methods We retrospectively reviewed 438 renal calculi patients after PCNL from August 2015 to July 2016.Among them,there were 251 men and 187 women,the mean age was (49.4 ± 11.1) years.The positive preoperative urine WBC,culture and nitrite rates were 29.7％ (130),12.1％ (53) and 15.1％ (66),respectively.The stone size was (851.2 ± 663.6) mm2,the stone CT value was (960.4 ± 303.4) HU,the operative time was (63.5 ± 33.4) min,124 (28.3 ％) were infection stones and multiple-tracts PCNL was performed in 69 (15.8％) patients.Univariate and multivariate logistic regression analysis were used to analyze perioperative predictors after PCNL.Results Thirty-nine patients developed SIRS (8.9％) after PCNL.The univariate analysis showed that positive preoperative urine WBC,nitrite,culture,operation time,stone size and transfusion had significantly impacts on the outcome of postoperative SIRS after PCNL (P ＜ 0.05).Multivariable logistic analysis showed that positive preoperative urine nitrite (OR =5.990,P ＜ 0.001),stone size (OR =2.251,P =0.027) and transfusion (OR =7.501,P =0.007) were independently related to the postoperative SIRS.Conclusion The positive preoperative urine nitrite,stone size and transfusion are independent risk factors for postoperative SIRS after PCNL.
