The correlation between the vitreomacular adhesion and exudative age-related macular degenerationa meta-analysis
10.3760/cma.j.issn.1005-1015.2017.06.017
- VernacularTitle:玻璃体黄斑粘连与渗出型老年性黄斑变性相关性的meta分析
- Author:
Jiwei TAO
1
;
Yiqi CHEN
;
Jianbo MAO
;
Yun ZHANG
;
Shixin ZHAO
;
Lijun SHEN
Author Information
1. 310020,温州医科大学附属眼视光医院杭州院区
- Keywords:
Wet macular degeneration/etiology;
Vitreous detachment;
Meta-analysis
- From:
Chinese Journal of Ocular Fundus Diseases
2017;33(6):626-630
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between the vitreomacular adhesion (VMA) and exudative age-related macular degeneration (AMD).Methods A literature research was performed in PubMed,EMbase,Cochrane Library,CNKI and Wanfang database from January 2000 to December 2016.Case-control studies on the relationship between VMA or posterior vitreous detachment and exudative AMD were included in this analysis.Literature screening and data extraction were performed according to inclusion and exclusion criteria.The qualities of the literatures were evaluated according to the Newcastle-Ottawa Scale (NOS).Seven literatures were selected into meta-analysis.The NOS score was 9 points in 1 article,8 scores in 4 articles,7 points in 2 articles.A total of 947 eyes with exudative AMD,638 eyes with dry AMD,and 618 eyes with controls were included.The correlation between exudative AMD and VMA were analyzed using the software Review manager 5.3.Results The prevalence of VMA in exudative AMD eyes was higher than that in controls [odds ratio (OR)=2.14,95％ confidence interval (CI)=1.19-3.84,P=0.010] and dry AMD eyes (OR=2.24,95％CI=1.24-4.03,P=0.007).There was no difference in PVD prevalence among exudative AMD eyes,dry AMD eyes (OR=0.44,95％CI=0.16-1.20,P=0.110) and controls (OR=0.70,95％CI=0.41-1.18,P=0.180).Conclusion There is correlation between VMA and exudative AMD.
