Analysis of clinical characteristics and prognosis of 27 cases of adverse reactions caused by Xuebijing injection
10.3760/cma.j.issn.1008-6706.2017.23.005
- VernacularTitle:血必净注射液不良反应27例分析
- Author:
Jianming ZHAO
1
;
Jianfang LIU
Author Information
1. 阳泉市第一人民医院药剂科
- Keywords:
Adverse druy reaction reporting systems;
Xuebijing injection;
Anaphylaxis
- From:
Chinese Journal of Primary Medicine and Pharmacy
2017;24(23):3537-3539
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the adverse reaction of Xuebijing injection and its prognosis.Methods 27 cases with adverse reactions caused by Xuebijing injection were collected.The clinical data,including medication time,dosage,combined medication,adverse reaction,clinical treatment and prognosis were analyzed.Results The dose of Xuebijing injection in 27 ADR patients were 10-50mL,mean (28.4 ± 4.3) mL.In 27 patients,males were significantly more than females(66.7％ vs.33.3％),40-70 years old patients were significantly higher than other age groups,the differences were statistically significant(x2 =6.000,20.691,all P ＜ 0.05).In 27 cases of adverse reactions,the highest proportion of skin in the involved organs was 48.1％,which was significantly higher than other organs,the difference was statistically significant(x2 =18.796,P ＜ 0.05).The highest proportion of 5-30min in adverse reaction time was 51.9％,which was significantly higher than that of less than 5min(25.9％) and 30min (22.2％),the difference was statistically significant (x2 =6.333,P ＜ 0.05).After stopping the treatment,the hormone,calcium gluconate,oxygen treatment and the expansion treatment,the patients all obviously improved or cured.The symptom disappearance time was 10minutes to 3 days,mean (39.5 ± 10.4) min.Conclusion The adverse reactions of Xuebijing injection are more common in men,and most of them are caused by the use of 5-30min.The highest proportion is skin involvement,the clinical work should pay attention to prevention and treatment.
