Observation of the clinical curative effect of flupentixol/melitracen combined with mosapride citrate in the treatment of functional dyspepsia
10.3760/cma.j.issn.1008-6706.2017.23.029
- VernacularTitle:氟哌噻吨美利曲辛联合枸橼酸莫沙必利治疗功能性消化不良临床疗效观察
- Author:
Wenguang WANG
1
;
Song ZHANG
Author Information
1. 诸暨市中心医院普内科
- Keywords:
Dyspepsia;
Flupentixol/melitracen;
Mosapride
- From:
Chinese Journal of Primary Medicine and Pharmacy
2017;24(23):3632-3636
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical curative effect of flupentixol/melitracen (deanxit) combined with mosapride citrate in the treatment of functional dyspepsia.Methods The clinical data of 240 patients with functional dyspepsia were collected,According to different treatment method,they were divided into two groups,120 patients of the control group were treated with mosapride citrate combined with omeprazole,120 patients of the observation group were treated with deanxit combined with mosapride citrate.One course of treatment was 4 weeks.After one course of treatment,the clinical curative effects and adverse reactions of the two groups were evaluated.Results After treatment,the abdominal distension,abdominal pain,early satiety,belching and other symptoms scores of the two groups were significantly lower compared with before treatment,the differences were statistically significant (all P ＜ 0.05).After treatment,the abdominal distension,abdominal pain,early satiety,belching and other symptoms scores of the observation group were significantly lower than those in the control group,the differences were statistically significant(all P ＜ 0.05).The clinical total effective rate of the observation group was 90.8％,which was significantly higher than 67.5 ％ of the control group,the difference was statistically significant (x2 =8.432,P ＜ 0.05).Before and after treatment,the liver and kidney function and blood in the urine routine examination in the two groups had no significant changes.The incidence rate of adverse reactions of the observation group was 11.67％,which of the control group was 15.83 ％,there was no statistically significant difference (x2 =0.911,P ＞ 0.05).Conclusion Deanxit combined with mosapride citrate in the treatment of functional dyspepsia is one of the important method,and its clinical effect is satisfactory,relatively safe,it is worthy of popularization and application.
