Report of bacterial resistance surveillance in Zhujiang Hospital in 2015
10.16718/j.1009-7708.2017.05.016
- VernacularTitle:2015年广州珠江医院细菌耐药性监测
- Author:
Liang FU
1
;
Lingxiao JIANG
;
Jun LONG
;
Changhong JIANG
;
Lijuan LIN
;
Yanping FANG
;
Nianyi ZENG
;
Nan YU
Author Information
1. 南方医科大学珠江医院检验医学部
- Keywords:
bacterial resistance surveillance;
antimicrobial susceptibility testing;
multi-drug resistant bacterium;
extensively-drug resistant bacillus;
methicillin-resistant Staphylococcus;
carbapenemase
- From:
Chinese Journal of Infection and Chemotherapy
2017;17(5):568-575
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the susceptibility profile of clinical isolates in Zhujiang Hospital in 2015.Methods Susceptibility test was carried out using Kirby-Bauer method or automated systems.Results A total of 4 229 clinical isolates were isolated from January to December 2015,including 2 688 (63.6％) gram negative and 1 541 (36.4％) gram positive bacteria.Methicillin-resistant S.aureus (MRSA) and coagulase-negative Staphylococcus (MRCNS) accounted for 47.2％ and 76.4％,respectively.The methicillin-resistant strains have much higher resistance rates to beta-lactams and other antimicrobial agents than methicillin-susceptible strains.Majority (94.0％) of MRSA strains were susceptible to trimethoprim-sulfamethoxazole,and 83.1％ MRCNS strains were susceptible to rifampin.No staphylococcal isolates were found resistant to vancomycin,teicoplanin or linezolid.E.faecalis strains showed much lower resistance rate to most of the drugs tested (except chloramphenicol) than E.faecium.No enterococcal isolates were found resistant to vancomycin or teicoplanin.ESBLs were produced in 52.6％ of E.coli and 39.7％ of Klebsiella (K.pneumoniae and K.oxytoca) strains.ESBLs-producing Enterobacteriaceae strains had higher resistance rates to common antimicrobial agents than non-ESBLs-producing strain.Enterobacteriaceae isolates were highly susceptible to carbapenems,(＜4％ resistant).Acinetobacter spp.strains showed high resistance to imipenem (69.2％ resistant) and meropenem (71.2％ resistant).Conclusions The antibiotic resistance is still increasing in this hospital.The emerging multi-drug or pan-drug resistant strains pose a serious threat to clinical practice and implies the importance of strengthening infection control.
