Clinical Observation of Guipu Shenqing Capsules Combined with Levofloxacin in the Treatment of Uri-nary Tract Infection
10.6039/j.issn.1001-0408.2017.33.12
- VernacularTitle:桂蒲肾清胶囊联合左氧氟沙星治疗尿路感染的临床观察
- Author:
Chengxuan LIU
1
;
Ying LI
;
Weijian XIONG
Author Information
1. 重庆市中医院
- Keywords:
Guipu shenqing capsules;
Levofloxacin;
Urinary tract infection;
Clinical observation;
Therapeutic efficacy
- From:
China Pharmacy
2017;28(33):4651-4653
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe clinical efficacy of Guipu shenqing capsules combined with Levofloxacin tablets in the treatment of urinary tract infection. METHODS:A total of 100 patients with urinary tract infection were randomly divided into ob-servation group (55 cases) and control group (45 cases). Observation group was given Levofloxacin tablet 0.1 g orally,twice a day+Guipu shenqing capsule 1.4 g orally,3 times a day;4 days later,they were given Guipu shenqing capsule alone for 3 d. Con-trol group was given Levofloxacin tablet 0.1 g orally,twice a day,same medication time as observation group+Placebo capsule 1.4 g orally,3 times a day. Both groups received treatment for 7 d. The infection efficiency,the change of frequent urination,urgent urination,dysuria,yellowish urine,integral,etiology efficacy and the occurrence of ADR were observed and compared between 2 groups. RESULTS:The response rate of injection(92.7%vs. 77.8%)and etiology(72.7%vs. 53.3%)in observation group were sig-nificantly higher than control group,with statistical significance(P<0.05). Before treatment,there was no statistical significance in the proportion of patients with dysuria,urgent urination,frequent urination or yellowish urine between 2 groups(P>0.05). After treatment,the proportion of patients in the item of zero point was significantly higher than before treatment,and the observation group was significantly higher than the control group;the proportion of patients in the item of six points was significantly higher than before treatment,and the observation group was significantly lower than the control group,with statistical significance(P<0.05). No obvious ADR was found in 2 groups during treatment. CONCLUSIONS:For urinary tract infection,Guipu shenqing cap-sules combined with Levofloxacin tablet can improve the anti-infection effect and relieve urinary irritation symptom with good safety.
