Effect of comprehensive intervention on the drug compliance in patients with hepatitis B virus-related hepatocellular carcinoma after receiving TACE
10.3969/j.issn.1008-794X.2017.10.017
- VernacularTitle:综合干预对乙肝病毒相关性肝癌TACE患者药物依从性的效果研究
- Author:
Guomei YOU
1
;
Guoliang SHAO
;
Fangying YANG
;
Ping ZHU
;
Gu ZHAO
;
Hui ZENG
;
Rui ZHANG
;
Lianqin MAO
;
Liyao XIA
Author Information
1. 310022,杭州 浙江省肿瘤医院介入科
- Keywords:
comprehensive intervention;
hepatitis B virus-related hepatocellular carcinoma;
transcatheter arterial chemoembolization;
drug compliance
- From:
Journal of Interventional Radiology
2017;26(10):931-934
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of comprehensive intervention led by nursing staffers on the drug compliance in patients with hepatitis B virus-related hepatocellular carcinoma (HCC) after receiving transcatheter arterial chemoembolization (TACE) treatment.Methods By using random sampling method,a total of 96 patients with hepatitis B virus-associated HCC,who had been treated with TACE and had taken nucleotide analogue drug for one month in the interventional department of a certain grade Ⅲ tumor hospital,were enrolled in this study.Under the premise of informed consent,comprehensive intervention,which was led by nursing staffers and was participated by both doctors and nurses,was conducted.Results After comprehensive intervention,the average score of drug compliance was (93.670±6.046) points,while the pre-intervention average score of drug compliance was (82.040±10.024) points,the difference between the two was statistically significant (P＜0.05).The ratio of patients who showed good drug compliance changed from pre-intervention 62.4％ to post-prevention 97.8％(P＜0.05).The post-prevention of patients,whose hepatitis B virus deoxyribonucleic acid (HBVDNA) level was within the normal range,was 45.16％,which was highcr than the pre-intervention ratio of 15.05％,the difference between the two was statistically significant (P＜0.05).Conclusion The comprehensive intervention led by nursing staffers can effectively improve the drug compliance in patients with hepatitis B virus-associated HCC after receiving TACE,and can reliably control serum HBVDNA level as well.
