Discussion on Spleen Deficiency as the Key Mechanism of Hepatitis B Virus Associated Glomerulonephritis
10.3969/j.issn.1005-5304.2017.12.029
- VernacularTitle:论脾虚是乙肝病毒相关性肾炎的关键机转
- Author:
zhen Yong XU
1
;
wei Shi RUAN
;
liang Yu QIU
Author Information
1. 福建中医药大学
- Keywords:
spleen deficiency;
mitochondrial injury;
hepatitis B virus associated glomerulonephritis;
mechanism
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2017;24(12):114-116
- CountryChina
- Language:Chinese
-
Abstract:
This article tried to discuss that spleen deficiency is the key mechanism of hepatitis B virus associated glomerulonephritis from TCM and Western medicine viewpoint. From the view of pathophysiology, energy metabolic disorder caused by mitochondrial injury and its series of damages are similar to symptoms caused by spleen deficiency appeared as yin fire and organs dystrophy, so mitochondrial injure belongs to spleen deficiency. And mitochondrial damage can further aggravate the virus replication of hepatitis B virus associated glomerulonephritis, causing damage to the kidney. Therefore, from the view of Western medicine, it can be known that spleen deficiency determines whether the liver function damage in the process of hepatitis B virus associated glomerulonephritis and lower energizer transformation. In terms of TCM, spleen deficiency plays an important role in all stages of the disease, and determines the outcome and prognosis of the disease. Therefore, this article proposed that the spleen deficiency is the mechanism of hepatitis B virus associated glomerulonephritis, which can provide references for clinic.