Progress of brucine and its preparations
10.3760/cma.j.issn.1006-9801.2017.11.017
- VernacularTitle:马钱子碱及其制剂研究进展
- Author:
Yinli ZHAO
1
Author Information
1. 056300,河北省武安市第一人民医院药剂科
- Keywords:
Anti-neoplastic angets,phytogenic;
Brucine;
Preparations;
Drug therapy
- From:
Cancer Research and Clinic
2017;29(11):784-788
- CountryChina
- Language:Chinese
-
Abstract:
The inhibiting mechanisms of brucine to cancer cells included inducing the apoptosis of cancer cells, inhibiting the proliferation of cancer cells, preventing cell adhesion and transfer. This paper reviews the function of brucine and its anti-tumor preparations, and compares the efficacy and adverse reactions between brucine related preparations and traditional drugs to evaluate its anti-tumor effects. Furthermore, more exploration on the inhibiting mechanisms is necessary for the patients to obtain safe and effective drugs.