The role of glutamate and peptidoglycan in nanotubes formation between adjacent bacteria
10.3969/j.issn.1002-2694.2017.10.008
- VernacularTitle:谷氨酸和肽聚糖在促进细菌间纳米管形成中作用的研究
- Author:
shi Qiao ZHONG
1
;
ping Ya HANG
;
lin Yan LIU
;
Hui DING
;
Feng YU
;
hui Yan CHEN
;
hua Long HU
Author Information
1. 南昌大学第二附属医院检验科
- Keywords:
nanotubes;
glutamic;
peptidoglycan
- From:
Chinese Journal of Zoonoses
2017;33(10):893-896
- CountryChina
- Language:Chinese
-
Abstract:
We investigated the formation mechanism and immediate constituents of nanotubes between adjacent bacteria,pre venting rapid increase of drug-resistant bacteria provide potential targets.We used scanning electron microscopy(SEM) to observe formation of nanotubes;glutamic was determined by surface desorption atmospheric pressure chemical ionization mass spectrometry(SDAPCI-MS)and peptidoglycan was determined by enzyme linked immunosorbent assay(ELISA) in the forma tion of nanotubes before and after.The results showed that Staphylococcus aureus and Escherichia coli consumed more glutamic after formation of nanotubes;at the same time,the concentration of peptidoglycan in nanotubes formation of S.aureus and E.coli increased significantly.This study illuminated the glutamic and peptidoglycanin role mechanism of nanotubes form.We found that peptidoglycan is constituents of nanotubes and glutamic is the main energy source for the formation of nanotubes.
