Pharmaceutical Care of One Case with Pulmonary Infection and Impaired Immune Function
10.3870/j.issn.1004-0781.2017.12.023
- VernacularTitle:1例免疫功能受损肺部感染患者的药学监护
- Author:
Jing WU
1
;
Wei TONG
;
Hong CHEN
;
Xingfu HUANG
;
Wanhua YANG
;
Jie FANG
Author Information
1. 杭州市妇产科医院药剂科
- Keywords:
Pharmaceutical care;
Impaired immune function;
Infection;
Lung;
Clinical pharmacist
- From:
Herald of Medicine
2017;36(12):1422-1425
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the mode and effects of clinical pharmacists participating in clinical treatment and providing pharmaceutical care. Methods The clinical pharmacists participated in the treatment of the case of thymoma complicated with pulmonary infection in respiratory intensive care unit (RICU),associated with the myasthenia gravis (MG), pure red cell aplasia (PRCA) and lower extremity deep vein thrombolysis (LEDVT),through adjustment of drug regimen, observation of curative effect,monitoring blood drug concentration and adverse reaction and interaction monitoring,which could give full play to the professional expertise of pharmacy,and contribute to the clinical rational drug use. Results For patients with impaired immune function complicated with pulmonary infection,the opportunistic infections require special attention,during the initial anti-infective therapy.When the patient was unable to tolerate high doses of sulfamethoxazole and trimethoprim (SMZ-TMP),the clinical pharmacist recommended to use caspofungin for the combined treatment of pneumocystis pneumonia.When voriconazole and cyclosporine A (CsA) were used at the same time,the blood drug concentration of CsA would be increased,due to drug interactions probably.To solve the problem,clinical pharmacists recommended a temporary reduction in CsA dose. Conclusion Clinical pharmacists use pharmaceutical expertise to help optimize clinical treatment regimens,can improve the safety and effectiveness of drug treatment.
