Value of contrast enhanced ultrasound combined with elastography in differential diagnosis of non-mass-like lesions on breast
10.3760/cma.j.issn.1008-1372.2017.10.013
- VernacularTitle:超声造影联合弹性成像对非肿块型乳腺病灶良恶性的诊断价值
- Author:
Ying CHANG
1
;
Jingchun YANG
;
Zhenpeng LENG
;
Lan DU
Author Information
1. 首都医科大学宣武医院超声诊断科
- Keywords:
Ultrasonography;
Elasticity imaging techniques;
Breast diseases/DI
- From:
Journal of Chinese Physician
2017;19(10):1504-1508
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diagnostic value of contrast enhanced ultrasound (CEUS),elastography and their combined use in diagnosing non-mass-like lesions on breast.Methods From November 2015 to January 2017,79 nodules diagnosed by conventional ultrasound were prospectively enrolled and examined by CEUS and elastography before surgery.Multivariate logistic regression models were established for CEUS and CEUS combined with elastography to diagnose breast malignancy.The diagnostic performances of CEUS,elastography and their combined use were evaluated with the receiver operating characteristic (ROC) curve.Results The CEUS features significantly predicting malignancy were hyperenhancement,heterogeneous enhancement,visualization of penetrating vessels (P ＜ 0.01).Furthermore,the multivariate logistic regression for CEUS combined with elastography showed that heterogeneous enhancement,visualization of penetrating vessels and elasticity score were the independent predictors of breast malignancy.The area under the ROC curve of CEUS combined with elastography was (0.915 ± 0.223),which was higher than that of CEUS and elatography (0.851 ±0.029,0.790 ±0.038,P ＜0.05).Moreover,the sensitivity,and accuracy of CEUS combined with elastography were 89.1％,and 86.1％,respectively.The omission diagnostic rate of CEUS combined with elastography (8.9％) was reduced.The diagnostic accuracy of CEUS combined with elastography was significantly higher than that of CEUS and elastography.Conclusions The diagnostic value of CEUS combined with elastography was remarkably significant in the differential diagnosis of non-mass-like lesions on breast.
