Preliminary results of the exposed dose of head,body and tail of the hippocampus in nasopharyngeal carcinoma patients treated with intensity modulated radiotherapy
10.3760/cma.j.issn.1004-4221.2017.11.003
- VernacularTitle:鼻咽癌IMRT海马头部、体部及尾部剂量分析
- Author:
Zongwen SUN
1
,
2
;
272100 济宁市第一人民医院肿瘤科
;
Lei SHI
;
Yue KONG
;
Fenglei DU
;
Tieming XIE
;
Yonghong HUA
;
Qiaoying HU
;
Xiaozhong CHEN
;
Yuanyuan CHEN
;
Ming CHEN
Author Information
1. 215004 苏州大学附属第二医院放疗科
2. 272100 济宁市第一人民医院肿瘤科
- Keywords:
Nasopharyngeal neoplasms/intensity modulated radiotherapy;
Radiotherapy dosage;
Hippocampus
- From:
Chinese Journal of Radiation Oncology
2017;26(11):1253-1258
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the radiation doses to the head, body, and tail of the hippocampus in intensity-modulated radiotherapy(IMRT)for nasopharyngeal carcinoma(NPC). Methods Ten NPC patients treated with IMRT were selected,and the head, body, and tail of both hippocampi were delineated on T1-weighted images. The doses to the hippocampus were then analyzed. WAIS-CR speech test results were tested by paired sample t-test. Results The mean doses to left and right hippocampi were 1 147±976 cGy and 1 011±602 cGy, respectively. The mean doses to the head, body, and tail of the left hippocampus were 1 739± 1 317 cGy, 890± 982 cGy, and 547± 688 cGy, respectively(P=0.042);the mean doses to the head,body,and tail of the right hippocampus were 1 691±942 cGy,744±483 cGy,and 531±603 cGy,respectively(P=0.002).The dose to the hippocampus decreased from the head to the tail, and the irradiated volume also decreased as the dose varied. Conclusions The dose to hippocampus decreases from the head to the tail in NPC patients treated with IMRT,which is worthy of attention.
