Frequency of cone beam computed tomography guidance in radiotherapy for nasopharyngeal carcinoma
10.3760/cma.j.issn.1004-4221.2017.11.004
- VernacularTitle:鼻咽癌放疗中CBCT引导的使用频率分析
- Author:
Xiaoyu LI
1
;
Renming ZHONG
;
Jidan ZHOU
;
Yanlong WU
;
Sen BAI
Author Information
1. 四川大学华西医院肿瘤中心 生物治疗国家重点 实验室放射物理技术中心
- Keywords:
Tomography;
X-ray computed;
Use frequency;
Nasopharyngeal neoplasms/radiotherapy
- From:
Chinese Journal of Radiation Oncology
2017;26(11):1259-1262
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze setup errors in cone beam computed tomography(CBCT)-guided radiotherapy for nasopharyngeal cancer(NPC)and evaluate the use frequency of CBCT. Methods Twenty-six patients newly diagnosed with NPC who received CBCT scan no less than 3 times per week during the whole course(7 weeks)of intensity-modulated radiotherapy(IMRT)were enrolled as subjects. Two setup errors were recorded each week:the setup error in the first CBCT analysis(Ef)and the setup error in the subsequent CBCT analysis(Ec). Comparisons of Efbetween two different weeks, Ecbetween two different weeks,and between Efand Ecin the same week were made by analysis of variance. Results During the 7 weeks,there were no significant differences in Efin the medial-lateral(ML), superior-inferior(SI), or anterior-posterior(AP)direction between any two weeks(all P>0.05);there were also no significant differences in Ecin the ML or SI direction between any two weeks(all P>0.05);there was a significant difference in Ecin the AP direction between two different weeks(P<0.05);there were no significant differences between Efand Ecin the ML or SI direction in any week(P>0.05);there were also no significant differences between Efand Ecin the AP direction in any week(P>0.05)except for the first week (P<0.05). Conclusions In IMRT for NPC,the setup errors in the ML and SI directions are stable in the whole course of radiotherapy,while the setup errors in the AP direction are different between the first week and subsequent weeks. Daily CBCT scan in the first week and weekly CBCT scan in the subsequent weeks are highly recommended for most patients to reduce the use frequency of CBCT.