Citrus peel extract and powder attenuate hypercholesterolemia and hyperglycemia using rodent experimental modeling
- Author:
Ashraf HUMAIRA
1
;
Butt Sadiq MASOOD
;
Iqbal Jawad MUHAMMAD
Author Information
1. National Institute of Food Science&Technology
- Keywords:
Functional foods;
Nutraceutical;
Citrus powder;
Hypercholesterolemia;
Hyperglycemia;
Efficacy study
- From:Asian Pacific Journal of Tropical Biomedicine
2017;7(10):870-880
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate hypocholesterolemic and hypoglycemic potential of citrus peel extract and powder using rodent experimental modeling. Methods: Considering the fact, rat feeding trial was carried out for a period of 56 d to access the prophylaxis of citrus peel flavonoids by employing normal (study I), hyperglycemic (study II) and hypercholesterolemic (study III) rats. Each study was further divided into three groups to ensure the provision of selected diets, i.e., control, functional and nutraceutical diets. Each study was further divided into three groups to ensure the provision of selected diets, i.e., control, functional and nutra-ceutical diets. Results: Declining trend for total cholesterol was observed in all studies with maximum reduction(8.55%)in rat group fed on nutraceutical diet in study III.Likewise,levels of low density lipoproteins and triglycerides reduced 11.39% and 7.89% respectively in hypercholesterolemic rats. Moreover, nutraceutical diet alleviated the sera glucose level by 8.96% in study II. Conclusions: Conclusively,inclusion of citrus peel bioflavonoids in dietary therapies is a promising strategy to modulate lipidemic and glycemic attributes without imparting any deleterious effect on hematological parameters.
