Significance of computed tomography and 3.0 T magnetic resonance imaging in intensity-modulated radiotherapy for esophageal carcinoma
10.3760/cma.j.issn.1004-4221.2017.11.007
- VernacularTitle:CT及3.0T MRI在食管癌IMRT中的价值
- Author:
Yifan HUANG
1
;
Liting QIAN
;
Jieping ZHOU
;
Jin GAO
;
Zhenchao TAO
;
Yan ZHOU
;
Liping YANG
;
Jian HE
;
Jing YANG
;
Yangyang RU
;
Zhang WANG
Author Information
1. 安徽省肿瘤医院/安徽省立医院西区放疗科
- Keywords:
Tomography;
X-ray computed;
Magnetic resonance imaging;
Oesophageal neoplasms/intensity-modulated radiotherapy
- From:
Chinese Journal of Radiation Oncology
2017;26(11):1276-1279
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the significance of computed tomography(CT)and 3.0 T magnetic resonance imaging(MRI)in intensity-modulated radiotherapy(IMRT)for esophageal carcinoma. Methods Thirty-five patients newly diagnosed with esophageal carcinoma who received radical radiotherapy in our hospital from November 2013 to April 2015 were enrolled as subjects. Target volume was delineated on the CT images and MRI images(T2-weighted and diffusion-weighted fusion images). The MRI-and CT-based IMRT plans were designed using the same dose prescription and dose constraints for organs at risk(OAR). The target volume,prescribed dose,and doses for OAR were compared between the two plans. Results In the two plans, dose distribution and planning parameters met the clinical requirement. The length of lesion,gross tumor volume (GTV),and planning target volume(PTV)defined by 3.0 T MRI were significantly smaller than those defined by CT(P=0.00,0.03,0.03). There were no significant differences in the D 2%,D 98%,D 50%,homogeneity index,or conformity index for primary GTV(PGTV)and PTV-PGTV between the two plans(all P>0.05). Compared with the CT-based plan,the 3.0 T MRI-based plan had a significantly smaller mean dose to the lungs and an insignificantly smaller actual dose to the lungs(P=0.00;P>0.05).There were no significant differences in maximum doses tolerated by the spinal cord or heart between the two plans. Conclusions In terms of target volume delineation and dosimetric parameters, both CT-and 3.0 T MRI-based plans meet the clinical requirement. The 3.0 T MRI-based plan may provide potential benefits for some OAR due to a smaller target volume compared with the CT-based plan.
