Clinical value of serum β-HCG detection in the diagnosis of abnormal pregnancy
10.3760/cma.j.issn.1008-6706.2017.21.022
- VernacularTitle:人绒毛促性腺激素检测用于非正常妊娠的价值研究
- Author:
Baiqun WU
1
;
Wenhui BIAN
Author Information
1. 慈溪市妇幼保健医院妇科
- Keywords:
Human chorionic gonadotrop;
Progesterone;
Estradiol 2
- From:
Chinese Journal of Primary Medicine and Pharmacy
2017;24(21):3286-3289
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of serum human chorionic gonadotropin (β-HCG) and progesterone (P) levels in the early diagnosis for abnormal pregnancy.Methods 53 cases with abnormal pregnancy and 30 normal pregnancy women were enrolled from Sep.2009 to Dec.2014 in our hospital.The automated chemiluminescent microparticle was used to detect the levels of β-HCG and P in serum,then analyzed the results.Results The expression of P was not associated with gestational weeks both in the normal and abnormal pregnancy patients on the day of admission (t =10.42,P ＜0.05),while the expression of β-HCG was increased with gestational weeks,and the difference was statistically significant (t =7.98,P ＜ 0.05).The level of E2 in both two groups had slight elevated with the gestational factors (t =0.43,P ＞ 0.05).Despite of gestational factors,the levels of E2/β-HCG and P in abnormal pregnancy group were lower than those in normal pregnancy group,the differences were statistically significant (all P ＜ 0.05).Analysis of the effective rate of conservative treatment for abnormal pregnancy patients,and it showed that success rate was 73.81％.Further analysis showed that the expression of β-HCG was not different in the success group and failure group (t =0.382,P ＞ 0.05),while the levels of P and E2 were much higher in success group than those in failure group with significant difference (t =9.431,6.792,all P ＜ 0.05).It showed that 12 ng/mL was the best one with perfect diagnosis value,and it could be used as an important index to evaluate the suitability of conservative treatment for abnormal pregnancy patients.Conclusion The levels of E2/β-HCG and P in serum can be used as important predictors in clinical diagnosis of abnormal pregnancy patients.
