Treatment experience of acute paraquat poisoning: analysis of 87 cases

VernacularTitle:急性百草枯中毒87例救治分析
Author: Shichao CHEN ¹ ; Baoquan SUN ; Jun LI ; Zhongkai YU ; Bo ZHAO
Author Information

1. 聊城市人民医院急诊科
Keywords: Paraquat,Poisoning; Therapy; Progrosis
From: Chinese Journal of Primary Medicine and Pharmacy 2017;24(21):3307-3310
CountryChina
Language:Chinese
Abstract: Objective To explore the treatment experience of acute paraquat poisoning,thus to explore the prognostic factors and treatment measures.Methods The clinical data of 87 patients with paraquat poisoning who were treated with combined therapy in our hospital emergency department 2014-2015 were retrospectively analyzed.Results 49 cases survived and 38 cases were died in 87 paraquat poisoning patients,the survival rate was 56.32％.The average paraquat of the death group was 65.3mL,which was significantly higher than 41.2mL of the survival group(t =16.65,P ＜ 0.01).Conclusion Amount of poisoning is the key to the prognosis,white blood cells were significantly increased,early or large areas of lung disease is an important factor in poor prognosis;early gastric lavage,cathartic and timely blood purification,application of adrenal cortex hormones,antioxidant and other comprehensive treatment can reduce mortality.