Liquid chromatography-mass spectrometry in laboratory medicine:why,what,and how
10.3760/cma.j.issn.1009-9158.2017.10.002
- VernacularTitle:液质联用在临床检验:为何?是何?如何?
- Author:
Yu ZHOU
1
;
Sihe WANG
Author Information
1. Department of Laboratory Medicine
- Keywords:
Chromatography;
liquid;
Mass spectrometry;
Clinical laboratory techniques
- From:
Chinese Journal of Laboratory Medicine
2017;40(10):737-740
- CountryChina
- Language:Chinese
-
Abstract:
In the era of precision medicine,liquid chromatography-mass spectrometry(LC-MS)will continue to have significant impact on laboratory medicine in spite of the inherent challenges posed by the technology.It seeks to explain what is clinical mass spectrometry,and describes its basic framework and life cycle.It concludeds the key points of clinical LC-MS through the practical experiences of CLSI guideline and Cleveland health care clinical mass spectrometry laboratory.It then illustrates the challenges of appropriately applying LC-MS to clinical diagnostics through comparisons with research based LC-MS utilizations. Furthermore,It attempts to elucidate the challenges and endeavors It has made toward implementing clinical LC-MS in China.Finally,It discusses the prospective future of LC-MS in clinical diagnostics.
