Protective Effect of Blueberry Anthocyanins on Oxidative Stress Injury by H2O2 of Human Umbilical Vein Endothelial Cells
10.11969/j.issn.1673-548X.2017.10.029
- VernacularTitle:蓝莓花青素对由H2O2诱导人脐静脉内皮细胞氧化应激损伤的保护作用
- Author:
Kai ZHAO
1
;
Yuanqiang ZHENG
;
Yuchen JIA
Author Information
1. 010030,呼和浩特市第一医院
- Keywords:
Blueberry anthocyanins;
Oxidative stress injury;
Human umbilical vein endothelial cells
- From:
Journal of Medical Research
2017;46(10):113-115
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the protective effect of blueberry anthocyanins on H2O2 induced human umbilical vein endothelial cells,HUVECs.Methods The cultured cells were divided into 3 groups:normal control group,H2O2 model group,blueberry anthocyanins group.MTT method was used to observe cell viability.Annexin V-FITC/PI straining was used to observe cell apoptosis.Flow cytometry was used to detect cell cycle.Results H2O2could induce HUVECs oxidative stress injury.Cell survival rate was positive correlated with drug concentration and action time.In the certain concentration range blueberry anthocyanin had a protective effect.Conclusion Blueberry anthocyanin can protect H2O2induced oxidative stress injury in HUVECs.
