Clinical Comparison Between Very-late Stent Thrombosis and Very-late In-stent Restenosis
10.3969/j.issn.1000-3614.2017.11.004
- VernacularTitle:极晚期支架内血栓与支架内再狭窄患者的临床对比分析
- Author:
Qiang CHEN
1
;
Dong SHEN
;
sheng Dang HUANG
;
sheng Jian JI
;
fei Fei YANG
;
ling Ling MA
;
hua Jin GUO
;
hong Chun ZHANG
;
Miao TIAN
;
wei Li ZHANG
Author Information
1. 中国人民解放军总医院第一附属医院 心内科
- Keywords:
Coronary artery disease;
In-stent thrombosis;
Coronary restenosis
- From:
Chinese Circulation Journal
2017;32(11):1056-1059
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To compare the clinical features between very late stent thrombosis (VLST) and very late in-stent restenosis, to discuss the potential risk factors for VLST occurrence. Methods: Our research included in 2 groups: VLST group, 21 ACS patients with coronary angiography (CAG) confirmed VLST admitted in our hospital and Control group, 38 ACS patients with CAG confirmed very late in-stent restenosis at same period of time. Basic clinical data, laboratory tests and relevant examinations were compared between 2 groups; potential risk factors for VLST occurrence were studied by Logistic regression analysis. Results: ① There were 8 (38.1%) patients discontinued anti-platelet therapy in a month by themselves in VLST group and 5 (13.2%) in Control group, P=0.03. ② 13 (61.9%) patients presented as ST-segment elevation myocardial infarction (STEMI) in VLST group, while all (100%) patients presented as Non-ST-segment elevation ACS (NST-ACS) in Control group, P<0.001. ③ The age, gender, previous histories of hypertension, diabetes, MI, smoking and interventional therapy were similar between 2 groups, P>0.05. ④ Compared with Control group, VLST group had decreased LVEF, P=0.001, increased peak values of TnI and NT-pro BNP, elevated WBC and hs-CRP, all P<0.001. ⑤ The index of echocardiography, blood lipid profiles, glucose and creatinine were similar between 2 groups, P>0.05. ⑥ Logistic regression analysis showed that discontinued anti-platelet therapy, elevated NT-pro BNP and hs-CRP were the independent risk factors for VLST occurrence, P<0.05. Conclusion: VLST may have life-threatening clinical features, insisted anti-platelet therapy and improved cardiac function could reduce VLST occurrence.
