Research progress of laboratory detective algorithms for syphilis
10.3760/cma.j.issn.1009-9158.2017.11.015
- VernacularTitle:梅毒实验诊断程序研究进展
- Author:
Manli TONG
1
;
Lili LIU
;
Lirong LIN
;
Huilin ZHANG
;
Tianci YANG
Author Information
1. 361004,厦门大学附属中山医院检验科 厦门大学医学院传染病研究所
- Keywords:
Syphilis;
non-Treponemal test;
Treponemal-specific test;
Traditional algorithm;
Reverse algorithm
- From:
Chinese Journal of Laboratory Medicine
2017;40(11):898-903
- CountryChina
- Language:Chinese
-
Abstract:
Syphilis can not be cultured in vitro.So far, serologic testing is still regarded as the mainstay for diagnosing syphilis and for monitoring the efficacy of subsequent antibiotic treatment.However, single serological tests have limitations in sensitivity or specificity.Detective algorithms with two or more serological methods will help to improve the effectiveness of syphilis diagnosis, and decrease missed diagnosis and misdiagnosis.This article will review advances on etiological examination, serological tests, and detective algorithms for syphilis.In particular, it specially introduces the merits and demerits of three detective algorithms for syphilis,so as to explore suitable screening methods,and provide basis for relevant administrative departments to formulate related laws, regulations and guidelines for syphilis.
