Genetic Polymorphisms of 17 Y-STR Loci in Nantong Han Population
10.3969/j.issn.1004-5619.2017.04.011
- VernacularTitle:南通汉族人群17个Y-STR基因座的遗传多态性
- Author:
Min YANG
1
;
xian Si XU
;
yan Hai QIN
;
Hao ZHAGN
;
Hai YI
;
jun Hai HAN
;
tao Dong JIA
;
hong Yu ZHANG
;
lin Shi LI
Author Information
1. 复旦大学生命科学学院
- Keywords:
forensic genetics;
polymorphism,genetic;
Y chromosome;
short tandem repeat;
Han population;
Nantong
- From:
Journal of Forensic Medicine
2017;33(4):383-387
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the genetic phenotypes of Nantong Han population and evaluate the application value of 17 Y-STR loci in Nantong population.Methods The peripheral blood samples were collected from 343 unrelated Nantong Han males and the genomic DNA were extracted by Chelex-100 method.Genotyping was performed using the AmpF(l)STR YfilerTM Kit.The results were compared with other 12 Han populations,including Anhui,Jiangsu,Jiangxi,Shandong,Shanghai,Zhejiang (1),Lanzhou,Nanyang,Luzhou,Mudanjiang,Shanxi and Zhejiang (2),and 9 minority populations (Mongol,Xibe,Tibetan in Lhasa,Tibetan in Qinghai,Kazak,Uighur,Manchu,Paiwan in Taiwan and Tujia).Results A total of 327 different haplotypes were found in 17 Y-STR loci in Nantong Han population.The haplotype diversity (HD) was 0.999 7.The R,value between Nantong Han and other Chinese populations ranged from-0.000 6 to 0.263 5.The multidimensional scaling results showed that Nantong Han population had no significant differences between most of the Han populations,but had significant differences between most of Chinese minority populations.Conclusion Seventeen Y-STR loci can be a powerful tool for forensic application because of its high polymorphism in Nantong Han population.
