Polymorphisms of 19 STR Loci in Guizhou Han Population and Their Forensic Application
10.3969/j.issn.1004-5619.2017.04.012
- VernacularTitle:贵州汉族19个STR基因座多态性及法医学应用
- Author:
song Qin ZHAO
1
;
Zheng REN
;
ling Hong ZHANG
;
lin Jia DAI
;
Jie WANG
;
Fang YU
;
Jiang HUANG
Author Information
1. 贵州医科大学法医学院
- Keywords:
forensic genetics;
polymorphism,genetics;
short tandem repeat;
GoldeneyeTM DNA ID 20A Kit;
Han population;
Guizhou
- From:Journal of Forensic Medicine
2017;33(4):388-392
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the allelic distribution of 19 autosomal STR loci in Guizhou Han population,and to estimate the forensic application value.Methods The 19 autosomal STR loci in 520 unrelated healthy individuals from Guizhou Han population were studied using GoldeneyeTM 20A kit.The 310 genetic analyzer was used for capillary electrophoresis,and the GeneMapper(R) ID v3.1 for genotyping.Results The heterozygosis,the discrimination power,the probability of exclusion,the polymorphism information content,the cumulative discrimination power and the cumulative probability of exclusion of the 19 STR loci were 0.603 8-0.9164,0.7900-0.985 6,0.295 5-0.8269,0.553 5-0.9089,1-1.2300×10-22 and 0.999 999 99,respectively.Compared with other five Han populations in pairwise allelic frequencies,Guizhou Han only had significant differences with Shandong Han,Liaoning Han and Shanxi Han.Conclusion The 19 autosomal STR loci such as D19S433 have a highly genetic polymorphic in Guizhou Han population,which have application values in the researches of population genetics and forensic genetics.
