Research Progress of PLA2R and anti-PLA2R Antibodies in Membranous Nephropathy
10.3969/j.issn.1671-7414.2017.05.043
- VernacularTitle:PLA2R和抗PLA2R抗体在膜性肾病中的研究进展
- Author:
ying Si LI
1
;
ping Zhi ZHANG
;
Jing YU
;
Feng LIU
Author Information
1. 吉林大学中日联谊医院肾内科
- Keywords:
phospholipase A2 receptor;
anti-phospholipase A2 receptor antibody;
membranous nephropathy
- From:
Journal of Modern Laboratory Medicine
2017;32(5):161-164
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,the phospholipase A2 receptor in membranous nephropathy as an antigen has been confirmed,people have a new understanding of the mechanism of membranous nephropathy.Abundant clinical trials showed anti-PLA2R antibody in membranous nephropathy formed the important pathogenic mechanism,and it's related to disease activity,result and prognosis,it can also predict the process of disease remission,even can help make treatments for patients.This paper gathered some progress locally and abroad to describe the anti-PLA2R antibody's in function membranous nephropathy.