Personalized biomechanical modeling of prostate deformation based on elastography for MRI three-dimensional transrectal ultrasound(TRUS)image registration
10.3760/cma.j.issn.1004-4477.2017.09.012
- VernacularTitle:结合超声弹性成像信息的前列腺个性化生物力学模型应用于经直肠三维超声与磁共振图像配准的价值
- Author:
Ming XU
1
;
Yi WANG
;
Chuan PENG
;
Xiaoer ZHANG
;
Xiaoju LI
;
Dong NI
;
Xiaoyan XIE
;
Mingde LYU
Author Information
1. 中山大学附属第一医院超声科 广东省超声诊断与介入治疗研究中心
- Keywords:
Elasticity imaging techniques;
Three-dimensional transrectal ultrasound;
Medical image registration;
Biomechanical model
- From:
Chinese Journal of Ultrasonography
2017;26(9):793-798
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical significance of personalized biomechanical modeling of prostate deformation based on ultrasound elastography for magnetic resonance imaging(MRI)-transrectal ultrasound(TRUS)image registration.Methods A total number of 5 patients and 1 commercial prostate phantom were imaged via transrectal ultrasound elastography,3D-TRUS and MRI from June 2016 to December 2016.A personalized biomechanical model via the patient-specific ultrasound elastography was made for the deformable registration of prostate MRI and 3D-TRUS images.The registration accuracy was evaluated by the target registration error(TRE)and also the t-test was conducted to validate the statistical significance of our results.Results All the 5 sets of patient data as well as the phantom data were successfully registered.The TRE value of the phantom data was 1.65 mm.The mean TRE value of 5 patients was 1.31 mm,compared with the 2.52 mm TRE value of the registration method without patient-specific biomechanical properties via elastography,was approximately 48% lower(P <0.05).Conclusions Personalized biomechanical modeling of prostate deformation based on ultrasound elastography for MRI-TRUS image registration possesses important clinical significance and is a promising way to provide more quality guidance and improve the accuracy of prostate biopsy.
