The early survival rate and its influencing factors of extremely premature and extremely low birth weight infants
10.3760/cma.j.issn.2096-2932.2017.06.001
- VernacularTitle:超未成熟儿和超低出生体重儿早期存活率及影响因素分析
- Author:
Dong CHEN
1
,
2
;
济南市儿童医院新生儿科
;
Zhaoe LIU
;
Yonghui YU
;
Feilin MA
;
Ruihua YU
;
Xiuwen XIE
;
Gang LI
Author Information
1. 250021 济南,山东大学附属省立医院新生儿科
2. 济南市儿童医院新生儿科
- Keywords:
Infant;
extremely low birth weight;
Survival rate;
Early onset sepsis;
Infant;
extremely premature;
Influence factors
- From:Chinese Journal of Neonatology
2017;32(6):401-405
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the early survival rate and its influencing factors of extremely preterm infants and extremely low birth weight ( ELBW ) infants.Method All extremely preterm infants and/or ELBW infants in Shandong Provincial Hospital from January , 2010 to December 2015 were studied retrospectively.The factors affecting their survival rate and their complications were analyzed retrospectively . All cases were assigned into the survival group and the death group .On the other hand , they were also assigned into two groups according to their birth , pre-2014 and post-2014.Result A total of 142 extremely preterm infants and/or ELBW infants were enrolled, their gestational age was 28 (27, 29) weeks, birth weight was 925 (830, 965) g.76 cases (53.5%) survived, 66 cases (46.5%) died.Factors associated with the survival rate were early onset sepsis , placental abruption , perinatal asphyxia , birth weight and pulmonary hemorrhage (P<0.05).There were 67 cases pre-2014 in which 30 cases survived (44.8%), while 75 cases post-2014 in which 46 cases survived ( 61.3%) .Comparative analysis between the two groups pre-2014 and post-2014 revealed that the survival rate was significantly different (χ2 =3.900, P=0.048).The top 2 underlying causes of death before 2014 were perinatal asphyxia and early onset sepsis . Furthermore, early onset infection became the first cause of death after 2014.Conclusion Along with the prevalence of neonatal resuscitation program and the optimization of respiratory support strategies in premature infants , the early survival rate of extremely preterm infants and /or ELBW infants has improved significantly.However, early onset sepsis may have been the crucial cause for their perinatal mortality .
