Clinical research of changes of oxygen saturation in intestinal tissues of preterm infants during erythrocyte infusion
10.3760/cma.j.issn.2096-2932.2017.06.008
- VernacularTitle:红细胞输注过程中早产儿肠道组织氧饱和度变化的临床研究
- Author:
Yunsu ZOU
1
;
Yang YANG
;
Yue WU
;
Yan GUO
;
Zhaolan CAO
;
Xiaoguang ZHOU
;
Rui CHENG
Author Information
1. 210008,南京医科大学附属儿童医院新生儿医疗中心
- Keywords:
Blood transfusion;
Enterocolitis;
necrotising;
Spectroscopy;
near-infrared;
Tissue oxygen saturation
- From:Chinese Journal of Neonatology
2017;32(6):435-438
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the variability of oxygen saturation in intestinal tissue of preterm infants during erythrocyte infusion .Method Preterm infants aged over 5 days, hospitalized in our NICU from March 2016 to August 2016 were selected by computer random number generator . Near-infrared spectroscopy was applied to monitor splanchnic tissue oxygen saturation ( SrSO2 ) and cerebral tissue oxygen saturation(CrSO2)during erythrocyte transfusion.The duration of transfusion was 4 hours.The mean value and range of SrSO2 and CrSO2 during transfusion were analyzed.To analysis the average and variable range of SrSO2 and CrSO2 and to illuminate the correlation with post-conceptional age. Result A total of 34 premature infants were collected.The average of SrSO2 was (0.56 ±0.06) and the average of CrSO2 was (0.62 ±0.02) throughout transfusion, There was a significantly greater change in SrSO2 than in CrSO2 during the transfusion period (0.35 ±0.14 vs.0.18 ±0.09) (P<0.05).The changing range of CrSO2 was smaller as the post-conceptional age increased , and was significant different statistically ( P=0.006). While there was little change in the range of SrSO 2 (P=0.191).Conclusion The of SrSO2 change was more significant than CrSO 2 in preterm infants during erythrocyte transfusion , which may cause ischemia-reperfusion injury to the intestinal tissue .It should be more cautious to avoid transfusion-related necrotizing enterocolitis.
