Progress in the application of mass spectrometry in reference measurement procedures
10.3760/cma.j.issn.1009-9158.2017.10.017
- VernacularTitle:质谱技术在参考测量程序中的应用进展
- Author:
Yi JU
1
;
Qing LI
;
Zhonggan JIN
;
Hewei SUN
Author Information
1. 200126,上海市临床检验中心
- Keywords:
Reference values;
Reference standards;
Mass spectrometry
- From:
Chinese Journal of Laboratory Medicine
2017;40(10):823-828
- CountryChina
- Language:Chinese
-
Abstract:
The establishment of laboratory medicine reference system is an important way for routine detection results to achieve traceability.The complete reference system consists of reference measurement procedures,reference materials and reference laboratories.The reference measurement procedure is usually characterized by a thorough study with a small measurement uncertainty.Based on the advantages of high specificity and high sensitivity in quantitative analysis, mass spectrometry plays an important role in the research of the reference measurement procedures in laboratory medicine.In the past 40 years, mass spectrometry technology has been more and more widely applied in medicine, electrolytes, metabolites and substrates, non-electrolyte metals, non-peptide hormones, protein and vitamin.It provides a powerful guarantee for the precise detection of these well-defined measureds.