Optimization of Water Extraction Technology for the Medicinal Materials in Compound Gastritis Capsule by Orthogonal Test
10.6039/j.issn.1001-0408.2017.31.30
- VernacularTitle:正交试验优化复方胃炎胶囊中药材的水提工艺
- Author:
Jiaoni ZHENG
1
;
Ling LIU
;
Daohui HE
Author Information
1. 重庆市急救医疗中心/重庆市第四人民医院药剂科
- Keywords:
Compound gastritis capsule;
Orthogonal test;
Extraction technology;
Paeoniflorin;
Salvianolic acid B
- From:
China Pharmacy
2017;28(31):4438-4440
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To optimize the water extraction technology for the medicinal materials in Compound gastritis cap-sule. METHODS:Orthogonal test was adopted. Using the comprehensive score of contents of paeoniflorin,salvianolic acid B and weight of dry extract as evaluation index,effects of adding water amount,decoction time and times on water extraction technology were investigated,and verification test was conducted. RESULTS:Optimized water extraction technology was as follows as decoct-ing for 3 times,120 min each time and adding 10-fold water each time. In verification test,average comprehensive score was 909.19(RSD=1.84%,n=3). CONCLUSIONS:Optimized water extraction technology is stable and feasible,and can be used for the water extraction for each medicinal material in Compound gastritis capsule.