Brain renin-angiotensin system: a potential therapeutic target for ischemic stroke
10.3760/cma.j.issn.1673-4165.2017.08.012
- VernacularTitle:脑肾素-血管紧张素系统:缺血性卒中的潜在治疗靶点
- Author:
Yanjun TIAN
1
;
Chuanxin LIU
;
Hui SUN
;
Yunlu JIANG
;
Hai LU
Author Information
1. 272067,济宁医学院山东省出生缺陷研究与转化协同创新中心
- Keywords:
Stroke;
Brain Ischemia;
Renin-Angiotensin System;
Angiotensin Ⅱ;
Receptor,Angiotensin,Type 1;
Receptor,Angiotensin,Type 2;
Peptide Fragments;
Neuroprotective Agents
- From:
International Journal of Cerebrovascular Diseases
2017;25(8):755-759
- CountryChina
- Language:Chinese
-
Abstract:
Brain renin-angiotensin system (RAS) is closely associated with many pathophysiological processes of cardiocerebrovascular diseases,including stroke.The activation of the different components in RAS will produce specific biological effects.This article reviews the roles of brain RAS in the pathophysiological processes of ischemic stroke,especially the neuroprotective effect of ACE2/Ang-(1-7)/Mas axis.
