A Meta-analysis of Clinical Efficacy for Enteral Nutrition vs Parenteral Nutrition in Critical illness
10.16151/j.1007-810x.2017.05.006
- VernacularTitle:肠内营养与肠外营养对危重症临床疗效的Meta分析
- Author:
Bin LIU
1
;
kai Wen BIN
;
mei Xiao CHEN
;
Hua HE
Author Information
1. 湘潭市中心医院重症医学科
- Keywords:
Enteral Nutrition;
Parenteral Nutrition;
Critical illness;
Meta-analysis
- From:Parenteral & Enteral Nutrition
2017;24(5):277-282
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To systematically evaluate the clinical efficacy of enteral nutrition (EN) versus parenteral nutrition(PN) on critically ill patient.Methods:Randomized controlled trials (RCT) comparing EN and TPN were searched in PubMed、Embase、Springerlink、Medline、CNKI、CHINAINFO and Vip from the date of database foundation to April 22,2016.The total complications,the total incidence of infections,pneumonia incidence,urinary tract infection occurrences,sepsis and other infection incidence,mortality,length of hospital stay,etc were collected.The quality and result of admission data were extracted by two researchers independently.Software RevMan5.3 was used to conduct meta-analysis.Results:Comparing parenteral nutrition,the results of meta-analysis show that enteral nutrition can significantly reduce total incidence of infections (OR =0.54,P =0.04)、pneumonia incidence (OR =0.65,P =0.04),and sepsis and other infection incidence (OR =0.59,P =0.04).The total incidence of complications,urinary tract infection rate,mortality and hospitalization time had no significant difference between enteral nutrition and parenteral nutrition.Conclusion:Enteral nutrition can significantly reduce the complications of infection for critically ill patients,especially the incidence of pneumonia,sepsis and other inflammatory reactions.
