Preoperative prognostic nutritional index predicts postoperative surgical site infections in patients with colorectal cancer
10.16151/j.1007-810X.2017.05.008
- VernacularTitle:预后营养指数在结直肠肿瘤术后手术部位感染的预测作用
- Author:
jun Jian WU
1
;
ming Chu ZHU
;
Jiang YAN
;
Xing WU
Author Information
1. 溧阳市人民医院普通外科
- Keywords:
PNI;
Colorectal cancer;
Surgical site infection
- From:Parenteral & Enteral Nutrition
2017;24(5):287-291
- CountryChina
- Language:Chinese
-
Abstract:
Objective:The purpose of this study was to explore the predictive value of PNI in surgical site infections (SSIs) for colorectal cancer patients undergoing enterectomies.Methods:A retrospective review of 332 colorectal cancer patients who underwent colorectal surgery between 2014 and 2015 was performed.Univariate and multivariate analyses were conducted to identify risk factors for SSIs,and receiver operating characteristic (ROC) cure was used to quantify the effectiveness of PNI.Results:SSIs were diagnosed in 43 (12.1％) patients,with incisional infection or deep incisional infection in 36 patients and organ/space infection in 7 patients.ROC curve analysis defined a PNI cut-off level of 48 corresponding to postoperative SSIs (area under the curve [AUC] =0.763,78.1 ％ sensitivity,62.7 ％ specificity).Furthermore,a multivariate analysis indicated that operation time ≥ 3 h (OR=3.42,95 ％ CI:1.22-8.78,P =0.04) and PNI ＜ 48 (OR=2.35,95％ CI:1.20-4.53,P =0.03) were independently associated with postoperative SSIs.Conclusion:Preoperative PNI is a simple and useful marker to predict SSIs in colorectal cancer patients after enterectomies.
