Advance in Bacteria Chemotaxis on Microfluidic Devices
10.11895/j.issn.0253-3820.170259
- VernacularTitle:基于微流控芯片的细菌趋化性检测研究进展
- Author:
Qian Xiao ZANG
1
;
Yu Zhe LI
;
Yan Xiao ZHANG
;
Lei JIANG
;
Qi Nan REN
;
Kai SUN
Author Information
1. 哈尔滨工业大学城市水资源与水环境国家重点实验室
- Keywords:
Macrofluidics;
Bacteria;
Chemotaxis;
Microenvironment;
Review
- From:
Chinese Journal of Analytical Chemistry
2017;45(11):1734-1744
- CountryChina
- Language:Chinese
-
Abstract:
Chemotaxis is the response ability of motile cells to chemicals gradients in environment and the migration toward higher concentration of chemoattractant or lower concentration of repellent. This mechanism is a basic nature of microorganisms to adapt to the environmental changes. The research of microbial chemotaxis is of great significance in utilizing bacteria to solve environment problems, control the pathogen infection, and develop microbial industrial projects. Microfluidic devices can realize qualitatively and quantitatively detect of bacterial chemotaxis. In comparison with traditional detect methods, microfluidic assay has an accurate control over bacterial microenvironment, with a higher sensitivity. In the past few years, bacterial chemotaxis study based on microfluidic assay was developed rapidly. In this paper, the microfluidic chemotaxis detectors that appeared in recent years were introduced from the aspect of chip structure, working principle and their applications. Finally, we provided insights into the challenges of bacterial chemotaxis and provided future perspectives.
