Research progress of microhaplotype in forensics
10.03618/j.issn.1001-5728.2017.05.011
- VernacularTitle:遗传标记微单倍型在法医学中的研究进展
- Author:
Peng CHEN
1
;
Jing ZHU
;
Youjing JIANG
;
Dan CHEN
;
Hui WANG
;
Jiong MAO
;
Weibo LIANG
;
Lin ZHANG
Author Information
1. 四川大学华西基础医学与法医学院
- Keywords:
forensic biological evidence;
microhaplotype;
genetic marker;
single nucleotide polymorphism(SNP)
- From:
Chinese Journal of Forensic Medicine
2017;32(5):484-487
- CountryChina
- Language:Chinese
-
Abstract:
Recently introduced microhaplotype has attracted more attention in forensic field. A microhaplotype is a short segment of DNA (e.g<200bp) contains two or more SNPs. The microhaplotypes showed extremely low mutation rates. The amplicons of alleles are balance to each other and without any stutters. By these advantages, it shows great value for forensic application, such as mixture stains analyzing, ancestor analysis, and kinship analysis. Thus, we aimed to review the development, analytical approach, nomenclature and population characteristic of microhaplotype.
