Advancement on the diagnosis of anaphylactic shock in forensic medicine
10.13618/j.issn.1001-5728.2017.04.006
- VernacularTitle:过敏性休克诊断的法医学研究进展
- Author:
Jinguo CHEN
1
;
Dongfang QIAO
;
Xia YUE
Author Information
1. 南方医科大学法医学院
- Keywords:
forensic pathology;
anaphylactic shock;
mast cell;
basophilic granulocyte;
IgE
- From:
Chinese Journal of Forensic Medicine
2017;32(4):359-362,367
- CountryChina
- Language:Chinese
-
Abstract:
It is still an important and hard work to diagnose anaphylactic shock in forensic practice. However, no breakthrough progresses in the diagnosis of anaphylactic shock and relevant research have been made so far due to the problems we used to meet in actual postmortem examination ,which are short of specific pathological changes in autopsy, the condition progress of patients who occur anaphylactic shock and history of allergy. Furthermore, patients suffer from diseases such as coronary heart disease, pneumonia, asthma, skin irritation, etc, and blood serum allergy biomarkers degrade after hemolysis on account of a long time from death to autopsy ,which are also the difficulties we have to cope with. The aim of this review is to focus on present situation and diagnostic index of anaphylactic shock including the pathological changes and some experimental methods such as special stain, immunohistochemical and serological test to provide reference for diagnosis and study of anaphylactic shock.