The prevalence of thyroid nodule in adults in high water iodine area
10.3760/cma.j.issn.2095-4255.2017.10.008
- VernacularTitle:水源性高碘地区成人甲状腺结节患病情况调查
- Author:
Junmin GUO
1
;
Qingping WANG
;
Xiangdong ZHANG
;
Baisuo GUO
;
Jie HUAN
;
Qingzhen JIA
Author Information
1. 山西省地方病防治研究所超声室
- Keywords:
Water;
Iodine;
Adult;
Thyroid nodule
- From:
Chinese Journal of Endemiology
2017;36(10):736-740
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevalence of thyroid nodules in the adults in high water iodine area and to reveal the risk factors of thyroid nodules.Methods Questionnaire investigation,determination of urinary iodine and thyroid ultrasound were carried out for residents aged 18 to 65 years old in Gaoche Village of Wenshui County in Shanxi Province,with the exception of pregnant and lactating women.Possible risk factors for thyroid nodules were analyzed.Results Of the 286 residents,89 cases of thyroid nodule were detected and the prevalence rate was 31.1％.The prevalence rate was 25.7％ (35/136) in male and 36.0％ (54/150) in female,there was no significant difference between sex (x2 =2.49,P ＞ 0.05).The average age of the cases with thyroid nodules was (49.6 ± 11.3) years old and was (43.5 ± 11.6) years old in cases without thyroid nodules,there was significant difference between age groups (t =4.11,P ＜ 0.05).The median of urinary iodine of the cases with thyroid nodules was 453.0 μg/L and was 408.4 μg/L in cases without thyroid nodules,there was no significant difference in the median of urinary iodine (Z =-0.616,P ＞ 0.05).The prevalence rate of solitary nodule was 57.3％ (51/89) and multiple nodules 42.7％ (38/89).As to the property nodule,the cyst nodule,the cyst-solid nodule and the solid nodule was 49.4％ (44/89),29.2％ (26/89) and 21.3％ (19/89),respectively.The results of Logistic regression showed that the prevalence of thyroid nodule increased with age (OR =1.048,95％CI:1.024-1.073,P ＜ 0.05) and the multiple nodule increased with age (OR =1.086,95％CI:1.044-1.129,P ＜ 0.05).The cyst nodule was a more common form in women (OR =2.559,95％CI:1.245-5.262,P ＜ 0.05).The prevalence of cyst-solid nodule increased with age (OR =1.125,95％CI:1.065-1.189,P ＜ 0.05).Conclusions The prevalence of the thyroid nodule in adults is high and the thyroid nodules are mainly the cyst nodules.The prevalence of the thyroid nodule is increased with age,especially the multiple nodules and the cyst-solid nodule in high water iodine area.The cyst nodule is a more common form in women.
