Clinical observation of acupuncture combined with theJintiange capsule in the treatment of lumbar disc herniation
10.3760/cma.j.issn.1673-4246.2018.01.007
- VernacularTitle:针灸联合金天格胶囊治疗腰椎间盘突出症临床研究
- Author:
Haijian MA
1
;
Min LI
;
Jinfeng LI
;
Pei WANG
Author Information
1. 101149,首都医科大学附属北京潞河医院针灸理疗科
- Keywords:
Intervertebral disc displacement;
Acupuncture analgesia;
Jintiange capsule;
Clinical study
- From:
International Journal of Traditional Chinese Medicine
2018;40(1):26-29
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical efficacy and safety of acupuncture combined with Jintiange capsule for the patients with lumbar disc herniation (LDH).Methods According to the random table method, 95 cases of patients with LDH were divided into the control group (n=47) and the research group (n=48) from June 2015 to March 2017. The patients in the control group were treated by acupuncture, while the patients in the research group were treated withJintiange capsule on the basis of the control group. The continuous treatment for 4 weeks was a course, and the treatment of two groups was 2 courses. The clinical total effective rate and symptom control time of two groups were observed. The pain intensity, JOA, the straight leg-raising angle and the serum level of inflammatory factors of two groups of patients were detected before and after treatment respectively. In addition, the incidence of adverse reactions of two groups was analyzed. Results The total clinical effectiveness of the research group was 93.75％ (45/48), and the control group was 76.60％ (36/47). The difference of two groups was statistically significant (χ2=5.562,P=0.018). The symptom control time (9.2 ± 2.3 dvs. 14.0 ± 2.3 d,t=-10.406) of the research group was significantly lower than that of the control group (P<0.05). After treatment, the straight leg-raising angle [(78.6 ± 17.6)°vs. (59.9 ± 3.2)°,t=5.869] and JOA (18.7 ± 2.1vs. 12.1 ± 1.9,t=16.152) of research group was significantly higher than those of the control group. While the VAS score (1.1 ± 0.3vs. 2.6 ± 0.6,t=-15.997), TNF-α (1.18 ± 0.22 ng/Lvs. 1.51 ± 0.21 ng/L,t=-7.476), IL-1β (25.14 ± 6.17 ng/mlvs. 40.26 ± 6.07 ng/ml,t=-12.038), IL-6 (93.85 ± 23.02μg/Lvs. 110.63 ± 24.07μg/L, t=-3.473) and TXB2 (299.36 ± 52.16 pg/mlvs. 429.17 ± 53.62 pg/ml,t=-11.961) of research group were significantly lower than those of the control group (P<0.05). Both groups had adverse events during the treatment.Conclusions Acupuncture combined withJintiange capsule could effectively improve the clinical symptoms, release pain and decrease the serum inflammatory factors of patients with LDH.
