Dosimetric analysis of CT-guided salvage interstitial brachytherapy for recurrent cervical cancer
10.3760/cma.j.issn.1004-4221.2018.01.015
- VernacularTitle:CT引导下宫颈复发癌挽救性组织间插植近距离治疗剂量学分析
- Author:
Zhongshan LIU
1
;
Jie GUO
;
Yangzhi ZHAO
;
Xia LIN
;
Zhiliang ZHANG
;
Hongyong WANG
;
Yunfeng LI
;
Xiaojun REN
;
Bingya ZHANG
;
Tiejun WANG
Author Information
1. 吉林大学第二医院肿瘤放疗科
- Keywords:
Cervical neoplasms/interstitial brachytherapy;
Dosimetry
- From:
Chinese Journal of Radiation Oncology
2018;27(1):74-78
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the dosimetric advantages of CT-guided interstitial brachytherapy for recurrent cervical cancer. Methods A total of 16 patients with recurrent cervical cancer after radical surgery and adjuvant external beam radiotherapy received interstitial brachytherapy with CT-guided implantation of metal needles. The high-risk clinical target volume (HR-CTV) was given 36 Gy in 6 fractions.D90for HR-CTV in the brachytherapy and the cumulative D2 cm3values for the bladder,rectum,and sigmoid colon in the previous external beam radiotherapy and the brachytherapy were analyzed.Results The mean D90value for HR-CTV was 52.5±3.3 Gy. The cumulative D2 cm3values for the bladder, rectum, and sigmoid colon were 85.6±5.8 Gy,71.6±6.4 Gy,and 69.6±5.9 Gy,respectively.The mean number of metal needles was 6.1±1.5 in each brachytherapy. The actual 1-year overall survival and local control were 81% and 69%, respectively. Conclusions CT-guided interstitial brachytherapy for recurrent cervical cancer shows good dose-volume histogram parameters and few complications, so it may be clinically feasible. However,its long-term clinical efficacy needs further observation.
