Role of annexin A5 in tumor and basic research on the target of it
10.3760/cma.j.issn.1673-422X.2017.11.009
- VernacularTitle:膜联蛋白A5在肿瘤中的作用及以其为靶点的基础研究
- Author:
Tengyang NI
1
;
Haibo WANG
;
Yanqing LIU
Author Information
1. 225001,扬州大学医药研究所
- Keywords:
Annexin A5;
Neoplasm invasiveness;
Neoplasm metastasis;
Signal transduction;
Immune tolerance
- From:
Journal of International Oncology
2017;44(11):842-845
- CountryChina
- Language:Chinese
-
Abstract:
As a key protein,annexin A5 involves in the process of invasion,metastasis and immune tolerance of tumors.And annexin A5 can not only promote the tumor,but also inhibit it.It has been widely concerned in the basic research targeting annexin AS.Because of the high affinity of annexin A5 for phosphatidylserine,annexin A5 is expected to be a new diagnostic marker and anti-tumor target.