Non-motor symptoms in Parkinson′s disease patients with different motor types

VernacularTitle:不同运动分型帕金森病患者的非运动症状分析
Author: Lingling ZHONG ¹ ; Yaqi SONG ; Hua CAO ; Keju JU ; Liang YU
Author Information

1. 南京医科大学附属淮安第一医院神经内科
Keywords: Parkinsons disease; Motor types; Non-motor symptom; Hoehn-Yahr classification; Tremor dominant
From: Chinese Journal of General Practitioners 2018;17(1):56-59
CountryChina
Language:Chinese
Abstract: One hundred ten patients with Parkinson′s disease(PD)and 110 age-matched healthy controls were enrolled in the study.The non-motor symptoms(NMS)were assessed with Non-motor symptoms of Parkinson′s disease questionnaire(PDNMSQ30).The PD patients were classified as gait abnormality posture type(PIGD, n=73)and tremor type(TD, n=37).The non-motor symptoms were compared between two groups.Results showed that the NMS in PD patients was higher than that in healthy controls[(35.2 ±3.0)vs.(6.0 ±2.0)symptoms, t=6.43, P=0.01].The NMS score of PIGD group was higher than that of TD group[(28.9 ±1.1)vs.(6.2 ±0.7)symptoms, t=2.73, P<0.01]; Mini-mental state examination(MMSE)and Montreal cognitive assessment scale(MoCA)scores of TD group were significantly higher than those of PIGD group(t=11.52,P<0.01; t=8.79,P<0.01).The results indicate that for PD patients with different motor types,their NMS are different,and PD patients with PIGD have more axial involvement,and more NMS.